ISSN: 2161-0932
Mahdi Akhbardeh
Tehran Medical University, Iran
Posters & Accepted Abstracts: Gynecol Obstet (Sunnyvale)
The relations between stress and non-hormonal cancers have been epidemiologically specified for many years, but there is an ambiguity considering etiological terms. Chronic stress is felt both directly and indirectly involved in the development of this disease. In the first case, chronic stress directly increases the inflammatory substances that cause the fracture of chromosomes chains and can be involved in the development of cancer. In the second case, there is an indirect and inverse relationship between increasing levels of chronic stress and the strength of the immune system. Chronic stress indirectly causes a decline in the influence of immune system by unknown reasons in two ways and it provides a platform for the development of disease: (1) It causes reduced cognitive lymphocytes and reduced discernment to distinguish between normal cells and cancer decreases; may be this could explain reason for the creation of a variety of immune disorders in patients with chronic stress; and (2) Reduced power of the immune system caused by chronic stress leads to the increased speed of the shortening of telomeres, which subsequently provides the platform for the breaking of the chromosomes. What is noteworthy is that whether the reduced power of immune system resulted from the increase in inflammation in the blood of the depressed people is due to the increased plasma levels of cortisol or it is eventually caused by other unknown reasons.
Email: mahdi_akhbardeh44@yahoo.com