Journal of Clinical and Experimental Ophthalmology

Journal of Clinical and Experimental Ophthalmology
Open Access

ISSN: 2155-9570

Is it rare or common? Bilateral optic nerve infiltration as an initial site of relapse of acute lymphoblastic leukemia in remission


18th Asia Pacific Ophthalmologists Annual Meeting

July 29-30, 2019 | Melbourne, Australia

Shew Fei Chee, Moon Yee Cheong and Mei Fong Chong

Hospital Raja Permaisuri Bainun, Malaysia

Posters & Accepted Abstracts: Clin Exp Ophthalmol

Abstract :

Case Report: A 13-years-old boy with acute lymphoblastic leukemia, incomplete remission, presented with both eyes blurring of vision for past two months. He also complained of sudden onset of monocular diplopia of third day duration. On examination, visual acuity of both eyes was 6/36. There was right cranial VI nerve palsy. Fundus examination showed bilateral optic disc oedema with dilated and tortuous veins over the disc. Lumbar puncture was done and there was no blast cell. We diagnosed him with bilateral optic disc swelling secondary to leukemic infiltration and chemotherapy was commenced. Unfortunately, his treatment was complicated by septicaemia with multiorgan failure which was fatal.

Conclusion: Optic nerve leukemic infiltration is a poor prognostic feature in relapse of acute lymphoblastic leukemia. Ophthalmic assessment is essential in patients with hematological malignancies as cytological analysis may not show any abnormality in early stage of relapse.

Biography :

E-mail: shewfei@gmail.com

 

Top