ISSN: 2155-9570
Shew Fei Chee, Moon Yee Cheong and Mei Fong Chong
Hospital Raja Permaisuri Bainun, Malaysia
Posters & Accepted Abstracts: Clin Exp Ophthalmol
Case Report: A 13-years-old boy with acute lymphoblastic leukemia, incomplete remission, presented with both eyes blurring
of vision for past two months. He also complained of sudden onset of monocular diplopia of third day duration. On examination,
visual acuity of both eyes was 6/36. There was right cranial VI nerve palsy. Fundus examination showed bilateral optic disc
oedema with dilated and tortuous veins over the disc. Lumbar puncture was done and there was no blast cell. We diagnosed
him with bilateral optic disc swelling secondary to leukemic infiltration and chemotherapy was commenced. Unfortunately, his
treatment was complicated by septicaemia with multiorgan failure which was fatal.
Conclusion: Optic nerve leukemic infiltration is a poor prognostic feature in relapse of acute lymphoblastic leukemia.
Ophthalmic assessment is essential in patients with hematological malignancies as cytological analysis may not show any
abnormality in early stage of relapse.
E-mail: shewfei@gmail.com