Journal of Sleep Disorders & Therapy
Open Access

Measurement of nasal NO and fractional exhaled NO in healthy children and patients with upper airway inflammatory disease

Annual Summit on Sleep Disorders & Medicine

August 10-12, 2015 San Francisco, USA

Dabo Liu, Zhenyun Huang and Yaping Huang

Women and Children�s MedicalCenter, Guangzhou, China

Posters-Accepted Abstracts: J Sleep Disord Ther

Abstract :

Objectives: To measure the nasal nitric oxide (NNO) and fractional exhaled nitric oxide (FeNO) in healthy children and patients with upper airway inflammatory disease and to discuss the clinical significance of these results. Methods: Fifteen healthy children, thirty cases of children with allergic rhinitis (AR), ten cases of children with non-allergic rhinitis, three cases of children with sinusitis and 30 cases of children with sleep disordered breathing (SDB) were enrolled. FeNO values and NNO values were measured non-invasively by using of NIOX MINO. IBM SPSS statistics 20.0 software was used to analyze the data. Results: NNO value and FeNO value were significantly increased in AR children compared with that in healthy children (Z=-4.449, P=0.000; Z=-5.427, P=0.000 respectively). NNO value was significantly increased in non-allergic rhinitis children compared with that in healthy children (Z=-2.552, P=0.011). NNO value was significantly increased in SDB children compared with that in healthy children (Z=-2.215, P=0.027). Conclusions: Our data support that NNO has a great value in monitoring upper airway inflammation. NNO and FeNO values of AR children those do not have typical symptoms of asthmaare significantly increased. This finding suggests that AR maybe evolved into asthma.

Biography :

Email: daboliu@126.com