ISSN: 2155-9600
+32 25889658
Charu Gupta, Dhan Prakash and Sneh Gupta
Amity University, India
RGPG College, India
Posters-Accepted Abstracts: J Nutr Food Sci
Obesity is a significant risk factor for major diseases-type II diabetes, coronary heart disease, hypertension and certain forms of cancer. The microorganisms in the form of probiotic bacteria can be used as a natural remedy for weight control, preventing obesity, and improving energy metabolism. Some strains of lactic acid bacteria (LAB) have the ability to lower serum cholesterol levels by breaking down bile in the gut, thus inhibiting its re-absorption. Lactobacillus (Lb. sporogenes and Lb. acidophilus NCFB 1748) and Bifidobacterium genus representatives play a critical role in weight regulation as an anti-obesity effect in experimental models and humans. Lactobacillus sporogenes has the ability to lower cholesterol levels by producing a significant reduction in low density lipoprotein (LDL) levels and a small but significant increase in high density lipoprotein (HDL) cholesterol; and the probiotic bacteria can also be successfully implanted in the intestine. Lactobacillus acidophilus is helpful in reducing serum cholesterol levels by reducing abdominal fat by 4.6%, and subcutaneous fat by 3.3%. The probiotic milk containing Lactobacillus gasseri SBT2055, significant decreases body weight BMI, waist circumference and hips. Researchers engineered a specific strain of Lactobacillus to produce a specific kind of fatty acid, t10, c12 CLA. Mice fed with the probiotic showed significant alterations to their fat tissues. Thus microbes have a tremendous potential and can be used in designing a nutraceutical for obesity and weight control.
Charu Gupta is an assistant professor for Amity Institute for Herbal Research & Studies at Amity University, India
Email: charumicro@gmail.com