Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Forough Kheiry
Islamic Azad University, Iran
Posters-Accepted Abstracts: J Clin Cell Immunol
Psoriasis is a common chronic skin disorder characterized by well-demarcated erythematous plaques with silvery scales (guttate, pustular, erythrodermic and inverse types); nail psoriasis, abnormal keratinocyte proliferation, increased dermal angiogenesis and systemic inflammation. Its prevalence is about 2ΓΆΒ?Β?4% worldwide and is associated with psoriatic arthritis, HLA-B27 syndromes, metabolic and cardiovascular diseases, uveitis, chronic kidney disease, vitiligo, osteoporosis, IBD and a higher risk of developing sudden sensory-neural hearing loss. The pathogenesis of psoriasis involves environmental, genetic and immunological factors. The treatment approaches still have several disadvantages such as being time-consuming, troublesome and disagreeable, or having potential side effects, resulting in non-adherence and frustration among patients. Some pharmaceutical treatments also result in negative effects, such as cardio-metabolic comorbidities and have significant interactions with drugs that are usually used to treat them. Therefore, patients need to have knowledge about beneficial dietary supplements, including the use of oral vitamin D, vitamin B12, selenium and omega-3 fatty acids in fish oils. Clinical improvement is possible by changing the dietary habits and lifestyle of the patients. On top of that, we introduce advanced nano-technological approaches for the efficient treatment of psoriasis. This review summarizes and compares the recent progress on findings, challenges and novel treatment approaches in psoriasis and psoriatic arthritis.
Email: foroogh_khorshid@yahoo.com