Journal of Medical & Surgical Pathology
Open Access
ISSN: 2472-4971
ISSN: 2472-4971
Alyssa Horvath
Massachusetts College of Pharmacy and Health Science, USA
Posters & Accepted Abstracts: J Med Surg Pathol
Statement of the Problem: Hyperlipidemia is one of the leading risk factors for heart disease, and an important parameter for the primary care provider to monitor in practice. Currently, the guideline for management of hyperlipidemia is outlined by the American College of Cardiology and the American Heart Association (ACC/ AHA). One of the critical questions for future guidelines set forth by the ACC/AHA is to examine the significance of non-HDL cholesterol in treatment decision-making for primary prevention of hyperlipidemia (ACC/AHA, 2013). Therefore, the purpose of the scholarly paper is to perform an integrative review of the literature of current quantitative research studies to compare the prognosis of non-HDL-C compared to LDL-C in cardiovascular disease risk in adults.
Findings: To obtain sufficient evidence to investigate the purpose of this study, an integrative review of the literature including a comprehensive search of quantitative research articles was performed by this author through several medical and nursing databases including CINAHL, Cochrane Library, Medline Ovid and PubMed. The theoretical orientation of this study is consistent with the health promotion model used in the primary care setting in primary and secondary prevention of chronic disease.
Conclusion & Significance: Multiple high-quality studies indicate non-HDL-C is superior to LDL cholesterol in predicting risk associated with CHD. The use of non-HDL-C in early identification of CHD risk allows the primary care provider to educate patients regarding health promotion and prescribe appropriate lipid-lowering therapy to prevent future adverse cardiovascular events.