Clinical & Experimental Cardiology
Open Access

Novel application of parameters in waveform contour analysis for assessing arterial stiffness in aged and atherosclerotic subjects

International Conference & Exhibition on Clinical Research Dermatology, Ophthalmology & Cardiology

5-6 July 2011 San Francisco, USA

Cheuk-Kwan Sun

Scientific Tracks Abstracts: JCEC

Abstract :

Although contour analysis of pulse waves has been proposed as a non-invasive means in assessing arterial stiffness in atherosclerosis, accurate determination of the conventional parameters is usually precluded by distorted waveforms in the aged and atherosclerotic objects. We aimed at testing reliable indices in these patient populations. Digital volume pulse (DVP) curve was obtained from 428 subjects recruited from a health screening program at a single medical centre from January 2007 to July 2008. Demographic data, blood pressure, and conventional parameters for contour analysis including pulse wave velocity (PWV), crest time (CT), stiffness index (SI), and reflection index (RI) were recorded. Two indices including normalized crest time (NCT) and crest time ratio (CTR) were also analysed and compared with the known parameters.