Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Robert Szuba and Piotr Tomczak
Posters-Accepted Abstracts: J Clin Exp Ophthalmol
The aim of the study was to reconstruct the optical conditions inside the diabetic crystalline lens. Optical parameters of
the crystalline lens were affected by homeostasis disorders associated with diabetes. The changes of optical parameters in
subjects with diabetes are usually described with statistical methods (1) and the results of these statistical analyses rarely provide
clear and unequivocal results. In the case of parameters that require high sensitivity measurements, the results often turn out
to be located at the borderline of statistical significance. Thus, in such cases it is necessary to use more stable and predictable
equivalents of these structures. For numerical simulations, a model of crystalline lens was constructed. The model was based
on geometric parameters (2), physiological data (3) with gradient index (GRIN) of optical medium of the lens (4). The GRIN
was modified according to our knowledge about changes of crystalline lens in diabetic patient (1). We examined refractive
power and spherical aberration and their changes for possible disturbances. The present study has shown that the changes of
gradient profile have the influence on the optical power of the lens and the value of spherical aberration as well. Furthermore,
the study has proved the possible reduction of changes of optical parameters of the lens due to swelling by GRIN. When the lens
swells, the focal length becomes shortened and spherical aberration is bigger. The results from simulation are clear because the
mathematical model proves the relationship between the geometry of the lens and GRIN and image reproduction.
Robert Szuba has done Bachelor and Master of Science in Physics and he is a PhD student of Biophysics. He is also a Faculty of Physics in Adam Mickiewicz University.