ISSN: 2155-9880
+44 1300 500008
Prerana Banerjee, J Fassl, M Grapow, F Eckstein and O Reuthebuch
University Hospital Basel, Switzerland
Scientific Tracks Abstracts: J Clin Exp Cardiolog
Majority of patients suffering from aortic valve stenosis are treated by aortic valve replacement or via transcatheter aortic
valve implantation. However, a subset of patients having severe comorbidities, such as renal insufficiency, severely
impaired ejection fraction, bicuspid aortic valve, large aortic annulus, ostial encroachment, redo-operation as well as severely
calcified porcelain aorta, have a relevant periprocedural risk. For this patient cohort an alternative treatment, aortic valve
bypass (AVB) with placement of a valved fabric graft between the left apex and descending aorta, is considered. Though
already developed in the early 1960ΓΆΒ?Β?s surgical acceptance was low due to the lack of appropriate instruments and the need
for cardiopulmonary bypass (CPB). However, with the development of a coring device (Correx, Inc., Waltham, MA, USA)
these impediments have been overcome. We report on a 72-year-old male patient suffering from severe low-flow-low-gradient
aortic valve stenosis (left ventricular ejection fraction 20%, mean pressure gradient 26 mmHg, valve orifice area 0.7 cm2).
Clinical symptoms were those of congestive heart failure. Previously the patient had undergone balloon valvuloplasty without
major improvement. On the basis of concomitant mutilating diagnosis the patient was rejected for conventional surgery and
transcatheter treatment. Thus AVB was suggested. The AVB consists of two components (a straight valve-containing conduit
with a porcine valve and an angled left ventricular connector) and bypasses the blood flow via the left ventricular apex into the
descending aorta. Perioperative course of our patient with implantation of the AVB without CPB was uneventful as was the
postoperative course. A magnetic resonance imaging of the heart on the fourteenth postoperative day demonstrated 55% of the
cardiac output passing via the conduit (2.6 l/min was measured in the descending aorta, 2.1 l/min in the ascending aorta). We
recommend off-pump AVB in patients with severe aortic stenosis when other therapy options are ruled out.
Recent Publications
1. Reuthebuch O, Fassl J, Brown J, Grapow M and Eckstein F (2013) Early experiences and in-hospital results with a novel
off-pump apico-aortic conduit. Interactive CardioVascular and Thoracic Surgery 16:482ΓΆΒ?Β?7.
2. Sarnoff S J, Donovan T J and Case R B (1955) The surgical relief of aortic stenosis by means of an apical-aortic valvular
anastomosis. Circulation 11:564ΓΆΒ?Β?75.
3. Elmistekawy E, Lapierre H, Mesana T and Ruel M (2010) Apico-aortic conduit for severe aortic stenosis: Technique,
applications and systemic review. Journal of the Saudi Heart Association 22(4):187ΓΆΒ?Β?94.
4. Vliek C J, Balaras E, Li S, Lin J Y, Young C A, De Filippi C R, et al. (2010) Early and midterm hemodynamics after aortic
valve bypass (apicoaortic conduit) surgery. The Annals of Thoracic Surgery 90:136ΓΆΒ?Β?43.
5. Adams C, Guo L R, Jones P M, Harle C, Brown J W and Gammie J S (2012) Automated coring and apical connector
insertion device for aortic valve bypass surgery. The Annals of Thoracic Surgery 93:290ΓΆΒ?Β?3.