Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Mohammed Azfar Siddiqui, Ibne Ahmad, Ekram Ullah, Mohd Khalid, Mehtab Ahmad, Mehtab Ahmad and Syed Amjad Ali Rizvi
Accepted Abstracts: Pediatr Therapeut
Purpose: To evaluate the abnormal antenatal umbilical cord coiling index (UCI) obtained during routine second trimester fetal anatomic survey as a predictor of adverse perinatal outcome. Method and materials: Th is prospective observational study was carried out on 150 consecutive women with uncomplicated, singleton pregnancy that had a routine second-trimester fetal morphology scan. Th e antenatal UCI was calculated as a reciprocal value of the distance between a pair of coils measured from inner edge of an arterial wall to the outer edge of the next. Th e coiling index was categorized as hypocoiled, normocoiled and hypercoiled. Th e abnormal umbilical cord coiling index was correlated with the following pregnancy outcomes: (1) small for gestational age (SFA) neonates, (2) mode of delivery, (3) presence of meconium-stained amniotic fl uid (MSAF), (4) Apgar scores at 1 minute, and (5) intrauterine deaths (IUDs). Statistical analysis was done using z- test and P-values < 0.05 was considered statistically signifi cant. Results: Out of 150 patients, only 120 patients were included in fi nal evaluation as they had all the data and adequate ultrasound images to meet the inclusion criteria. Hypercoiling was associated signifi cantly with interventional delivery (z=2.9; P< 0.05) and presence of MSAF (z=2.1; P< 0.05). Hypocoiling was associated signifi cantly with IUDs (z=3.2; P< 0.05). Hypocoiling was also associated with higher prevalence of SFA neonates, presence of MSAF, and low Apgar scores at 1 minute, but the association between them were not statistically signifi cant. Conclusion: Abnormal umbilical cord coiling index is associated with higher prevalence of interventional delivery, presence of MSAF, IUDs, SFA neonates, and low Apgar score at 1 minute. Th us abnormal umbilical cord coiling index can be used as promising prognostic marker for predicting adverse perinatal outcome. Further studies are needed to test this hypothesis.