Journal of Pharmaceutical Care & Health Systems
Open Access
ISSN: 2376-0419
+44 1300 500008
ISSN: 2376-0419
+44 1300 500008
Gerald H Tomkin
Diabetes Institute of Ireland, Ireland
Posters-Accepted Abstracts: J Pharma Care Health Sys
The cause of diabetes in the vast majority of patients is unknown, hence the division between type 1 and type 2 diabetes has little meaning in relation to chronic complications. Although hyperglycaemia is associated with both large and small vessel destruction, improvement in blood sugar control has shown in many studies, a reduction in progression of small vessel disease. It has been more difficult to demonstrate that reduction in blood sugar improves large vessel disease outcome. This literature will be reviewed. Reference will be made to studies that suggest that tight blood sugar control may be detremental to outcome. The place of the new oral hypoglycaemic drugs such as DPP4 inhibitors and the newer SGLT2 inhibitors will be discussed. Subcutaneous GLP1 agonists will also be discussed and newer drugs in the pipeline will be discussed. Emphesis will be placed on the development of newer hypoglycaemic agents which will be effective onthose patients who cannot manage lifestyle changes and weight reduction. Finally the effectiveness of low calorie diets and bariatric surgery in reversing diabetes will be examined. These studies demonstrating the need for effective drugs to alter the apetite centre.
Email: TOMKING@tcd.ie