Organic Chemistry: Current Research
Open Access

Recent achivements in the chemistry of five and six member ring nitrogen heterocycles

10^th European Organic Chemistry Congress

March 21-22, 2019 | Rome, Italy

Ionel I Mangalagiu, Violeta Mangalagiu, Dorina Mantu Amariucai, Ramona Danac, Costel Moldoveanu and Gheorghita Zbancioc

Alexandru Ioan Cuza University of Iasi, Romania

Scientific Tracks Abstracts: Organic Chem Curr Res

Abstract :

During the last fifty years, nitrogen heterocycles compounds have received considerable attention as highly valuable materials in the fields of pharmacy / medicine, opto-electronics and agriculture. As part of our ongoing research in the field of azaheterocycles derivatives, we present herein some core results obtained by our group in the field of nitrogen heterocycles derivatives, focused on chemistry and their pharmacological and industrial potential applications. The chemistry presented is straight and efficient, and focused in the area diazols, triazols, azine (and bis-azine), diazine (and bis-diazine), phenanthroline and related. Stereo- and regio- chemistry aspects are discussed. The chemistry involve both conventional (thermal heating) and nonconventional (microwave and ultrasounds) methods. Concerning pharmacological potential applications, our attention was focused in the area of obtaining compounds with anticancer, antimycobacterial, anti-leishmanial, and other antimicrobials activity. For the industrial potential applications our research was focused in obtaining of new chemical entities with fluorescent property, molecular devices (such as logic gates), chemosensors, growth regulators for plants, pesticides and insecticides, ionic liquids for synthetic uses.

Biography :

Ionel I Mangalagiu is a professor of organic and medicinal chemistry and Vice-Rector with research at Alexandru Ioan Cuza University of Iasi, Romania. Previously, prof. Mangalagiu served as Dean, Vice-Dean, Head of Organic Chemistry Department, etc. at Faculty of Chemistry. He has nearly 30 years of experience in the research, focused in the area of Heterocycles Compounds. He has over 150 papers, 13 patents, 3 international chapter books, etc. He was Visiting Professor and/or invited speaker to prestigious foreign universities (Ludwig Maximilianus University Munchen and Technische Universität Braunschweig, University of Florence, Universite D’Angers), awarded with numerous prizes and honours: DAAD and NATO award, “Costin D. Nenitescu Medal” (Romanian Society of Chemistry), “Al.I.Cuza University Award in Research”, Special Award of Croatian Association of Inventors, etc.