Clinical & Experimental Cardiology
Open Access

Role of Adiponectin in menopausal women

World Congress on Cardiology and Cardiac Surgery

May 16-17, 2018 | Montreal, Canada

Muhammad I K Afridi

Near East University, Turkey

Posters & Accepted Abstracts: J Clin Exp Cardiolog

Abstract :

Adipogenesis refers to the differentiation of pre-adipocytes into mature fat cells, i.e. the development of adipose tissue, which varies according to sex and age. Adipocytes differentiate from stellate or fusiform precursor cells of mesenchymal origin. Adiponectin has been postulated to act an important role in the modulation of glucose and lipid metabolism in insulin-sensitive tissue in both humans and animals. The transition from pre to post menopause is associated with the emergency of many features of metabolic state. The intraabdominal body fat increases, low density lipoprotein and triglyceride levels increase while high density lipoprotein decreases. As the results, to date are conflicting. In our study, we aimed to study the changes in adiponectin and anthropometric parameters after menopause. For this purpose, the ELISA methods were used in the study to evaluate the values of adiponectin. A total of 70 female in menopause and 90 control subjects were included in this study. The results showed that adiponectin, BMI and blood pressure increased with menopause and in order to investigate the effect of menopause on these parameters, further work must be carried out in the near future. ibrarneu@gmail.com