Journal of Chromatography & Separation Techniques
Open Access

Spectral studies, antimicrobial and antioxidant screening of (Z)-1-(5-bromo-2-hydroxyphenyl)-3-(4- fluorophenyl)-3-hydroxyprop-2-en-1-one

3^rd International Conference on Mass Spectrometry

October 10-11, 2016 Kuala Lumpur, Malaysia

Dayanand M Suryawanshi, Suresh T Gaikwad, Anjali S Rajbhoj and Amit S Waghmare

Rayat Shikshan Sanstha�s Annasaheb Awate College, India
Dr. Babasaheb Ambedkar Marathwada University, India
PVP College and Research Center, India

Posters & Accepted Abstracts: J Chromatogr Sep Tech

Abstract :

The synthesis of (Z)-1-(5-bromo-2-hydroxyphenyl)-3-(4-fluorophenyl)-3-hydroxyprop-2-en-1-one is of biologically importance. It has been synthesized by conventional as well as ultrasound irradiation method using substituted aromatic acids and substituted ortho-hydroxyl acetophenones employing Baker-Vankataraman transformation. Utilization of ultrasound irradiation, simple reaction conditions, isolation and purification make this manipulation very interesting from an economic and environmental perspective. The antibacterial, antifungal in vitro anti-oxidant screenings shows good results of its activities. The characterization of formed compounds was carried out by 1H-NMR, mass spectroscopy, 13C-NMR, UV/Visible spectroscopy, FTIR spectroscopy.

Biography :

Email: sdayanand77@gmail.com