Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
+44 1478 350008
ISSN: 2161-0495
+44 1478 350008
Marie-Agnes Opsomer
Bichat Claude Bernard Hospital, France
Posters & Accepted Abstracts: J Clin Toxicol
With the development of targeted therapies and specific preparation or administration increasingly diversified, we undertook the census biotherapy prepared in pharmaceutical technology unit (UP) and their delivery systems in service. The objective is to make recommendations and to standardize practices for the preparation and administration of preparations within the services. The criteria studied regarding preparations are proprietary name, laboratory fields of application and indications and protocols in oncology, the nature of reconstituting solvent, the nature and volume of dilution solvent, the shelf life after dilution, and storage conditions after reconstitution. The criteria studied regarding the administration are infusion duration, presence of joint administration of cytotoxic drugs, presence of filter in supply, inconsistency of the preparation with PVC and phthalates. Data collection is performed using the summaries of product characteristics. The results are presented in a summary table for an appropriation by the teams of the UP and care services. As regards the antibodies, 12 do not require coupling administration 6 of which require the presence of a 0.2 �¼m filter in supply administration. Adding a connection of Directors is aimed primarily at protecting nursing during administration. Also the decision to include a connection is correlated directly to the protocol type and the cytotoxicity of co-administered substances. This table shows the diversity of arrangements for preparation and administration of biotherapy. It will standardize administrative practices within our institution and optimize them by helping to reduce errors and inconsistencies related to preparations and mounting.
Email: ma.opsomer@gmail.com