Journal of Antivirals & Antiretrovirals
Open Access

The course of two viruses: HIV associated multicebtric Castleman�s disease

International Conference and Exhibition on VIROLOGY

5-7 September 2011 Baltimore, USA

Yohannie Billy Mlombe

Scientific Tracks Abstracts: JAA

Abstract :

Castleman�s disease was fi rst described by Dr. Benjamin Castleman in 1956. It is a benign and rare lymphoproliferative disorder. Th e two main forms are unicentric and multicentric Castleman�s disease. In HIV positive patients, available evidence points to HHV8 as the cause of multicentric Castleman�s disease. Th e synergism of HIV and HHV8 causes a number of common HIV associated diseases which may pose diagnostic challenges. In addition, HIV associated multicentric Castleman�s disease poses management challenges. Th is presentation discusses some of these challenges, specifi cally as relevant to Sub-Saharan Africa, in the light of current research questions about HIV and HHV8.