Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
+44 1300 500008
ISSN: 2155-9880
+44 1300 500008
Ada Yonath
Weizmann Institute of Science, Israel
Keynote: J Clin Exp Cardiolog
Resistance to antibiotics and the spread of antibiotics metabolites are severe problems in contemporary medicine and ecology. Structures of complexes of eubacterial-ribosomes with antibiotics paralyzing them illuminated common pathways in inhibitory-actions, synergism, differentiation and resistance. Recent structures of ribosomes from a multi-resistant pathogens identified features that can account for species-specific diversity in infectious-diseases susceptibility. These may lead to design of environmental-friendly degradable antibiotics, which will also be species-specific antibiotics-drugs, thus the basis for s revolution in the antibiotics field, which its current preference for wide-spectrum drugs. Thus, reducing resistance while protecting the environment and preserving the microbiome.
Ada Yonath is focusing on protein biosynthesis and the antibiotics hampering it. In the seventies she established the first structural-biology laboratory in Israel. She is the Director of Kimmelman Center for Biomolecular-Structure. During 1986-2004 she also headed Max-Planck-Research-Unit for Ribosome Structure in Hamburg. Among others, she is a member of US-National-Academy-of-Sciences; Israel Academy; German Science Academy; PontificiaAccademia-delle-Scienze (Vatican). She holds honorary doctorates from Oslo, NYU, Mount-Sinai, Oxford, Cambridge, Hamburg, Berlin-Technical, Patras, De-La-Salle, Xiamen, Lodz universities. Her awards include the Israel Prize; Louisa-Gross-Horwitz Prize; Linus-Pauling Gold Medal; Wolf-Prize; UNESCO/L’Oreal Award; Albert-Einstein World Award for Excellence; and Nobel Prize for Chemistry.
Email: Ada.Yonath@weizmann.ac.il