Organic Chemistry: Current Research
Open Access

Towards sustainability and molecular diversity by design of domino and multicatalytic strategies in N-Acyliminium ion chemistry

10^th European Organic Chemistry Congress

March 21-22, 2019 | Rome, Italy

Dalla Vincent

University of Le Havre, France

Scientific Tracks Abstracts: Organic Chem Curr Res

Abstract :

Over the last decade my research group developed some efficient catalytic methodologies in the area of N-acyliminium ion chemistry. Those methods are largely contingent to the use of Brønsted and Lewis superacidic catalysts of the triflate and triflimidate family to activate and enable effective alkylations of cyclic N,O-acetals as N-acyliminium precursors. Driven by the current societal stakes to develop sustainable chemistry with the respect of atom- and step economy principles as the guidelines, recently we particularly endeavored to integrate our catalytic N-acyliminium processes into more complex, sequential events. This talk will illustrate our efforts in designing cascade and multicatalytic transformations that provide a wide array of relatively sophisticated polyanellated structures from trivial cyclic N,O-acetals with general good efficiency.

Biography :

Dalla Vincent completed his PhD in 1994 at the University of Reims Champagne-Ardennes. In 1995 he was appointed “Maitre de Conferences” at the Ecole Nationale Supérieure de Chimie de Lille, and then in 1999 he moved to the University of Le Havre, where he became professor in 2008. His main research interests include the development of catalytic, stereoselective, and tandem reactions in N-acyliminium ion chemistry and their synthetic applications towards alkaloid type structures.