Pediatrics & Therapeutics
Open Access

Transforming growth factor beta-1 in human breast milk and its correlation with infants parameters

29^th International Conference on PEDIATRICS HEALTH

July 27, 2020 | Webinar

Jehan Alsharnoubi

Cairo University, Egypt

Posters & Accepted Abstracts: Pediatr Ther

Abstract :

Background: Breastfeeding provides optimal nutrition and health protection for the infant; it contains many anti-inflammatory factors, including transforming growth factor beta-1 (TGF-b1). Our study aimed to measure the level of TGF-b1 in human milk and to find its correlation with some infant anthropometric characteristics. Subjects and Methods: A milk sample was collected from 84 mothers and the level of TGF-b1 was measured using enzyme-linked immunosorbent assay. Results: TGF-b1 was significantly higher in vegetarian mothers compared with non-vegetarian mothers (p = 0.044). Additionally, the mean value of breast milk TGF-b1 was significantly higher in mothers using contraceptive pills compared with those who do not (p = 0.021). Also, the mean value of TGF-b1 was significantly higher in infants 3–6 months than those <3 months (p = 0.010); also there was a significant difference regarding infants’ weight and length with average weight and length (p = 0.042) and (p = 0.009), respectively. Conclusions: TGF-b1 in human milk may play a role in infants’ growth and development; mothers’ diet is known to influence TGF-b1 level and its relation to infants’ age and weight. Contraceptive method could have an influence on TGF-b1 levels during breastfeeding. Keywords: TGF-b1, Human milk, Infant anthropometric characteristics