Journal of Medical & Surgical Pathology
Open Access
ISSN: 2472-4971
ISSN: 2472-4971
E Devi Priya
Bharathiar University, India
Posters & Accepted Abstracts: J Med Surg Pathol
The unique material properties that appear at the nanoscale are called nanoparticles provides many benefits and new opportunities to address the complexity of cancer. The application of nanotechnology for the treatment of cancer is mostly based on early tumor detection and diagnosis by nano devices capable of selective targeting and delivery of chemotherapeutic drug to the specific tumor site. Historical attempts to improve nanoparticles homing to tumor cells have relied on enhanced permeability and retention EPR-effect to direct imaging and therapeutic agents to the cancer site. In order to maximize the diagnostic accuracy of nanoparticles imaging agent, it is essential to design in a manner, which maximizes its transport to a cancerous lesion.
Wealth materials which includes lipid, metals and polymer, enables the production of nanoparticles for many clinical imaging modalities eg: CT, MRI. It facilitate accurate diagnosis of cancer, increase contrast sensitive, early and accurate diagnosis of most aggressive forms of cancer, in vivo journey, ability to target at specific site and generate deductible signals. Nano particles can be used in two methods bio-physical and bio-chemical methods.
However, several years of investigation into the application of these materials to cancer research has revealed challenges that have delayed the successful applications of these agents to the field of biomedical imaging understanding these challenges is critical to take full advantage of the benefits offered by nano-sized imaging agents.