Current Synthetic and Systems Biology
Open Access

Charis Eng

Biography

Charis Eng, MD, PhD is the Chair and founding Director of the Genomic Medicine Institute of the Cleveland Clinic, founding Director and attending clinical cancer geneticist of the institute’s clinical component, the Center for Personalized Genetic Healthcare, and Professor and Vice Chairman of the Department of Genetics at Case Western Reserve University School of Medicine. She holds a joint appointment as Professor of Molecular Medicine at the Cleveland Clinic Lerner College of Medicine and is a member of Cleveland Clinic’s Taussig Cancer Center and of the CASE Comprehensive Cancer Center. Dr. Eng was honored with the Sondra J. and Stephen R. Hardis Endowed Chair in Cancer Genomic Medicine in 2008 and the American Cancer Society Clinical Research Professorship in 2009. More recently, she was elected to the National Academy of Medicine (previously known as Institute of Medicine) of the US National Academies of Sciences for her achievements and leadership in genetics- and genomics-based research and personalized healthcare. She continues to hold an honorary appointment at the University of Cambridge. Dr. Eng’s research interests may be broadly characterized as clinical cancer genetics translational research. Her work on RET testing in multiple endocrine neoplasia type 2 and characterization of the widening clinical spectra of PTEN mutations have been acknowledged as the paradigm for the practice of clinical cancer genetics. At the clinical interface, Dr. Eng is acknowledged as one of the rare “go to” people on what is and how to implement genetic

Research Interest

Cancer Genetics; Cancer Genomic Medicine; Cancer Research; Cancer Family History; Cancer Predisposition; Cancer Susceptibility; Heritable Cancer Syndromes; Cowden syndrome; Integrative Genomics; Cancer Metagenomics; Microbiome; Metabolome; Breast Cancer; Thyroid Cancer; Endocrine Cancer; Pheochromocytoma; Autism Research; PTEN; SDHA; SDHB; SDHC; SDHD; KLLN; KILLIN