Mass Spectrometry & Purification Techniques
Open Access

MALDI

MALDI is that the abbreviation for Matrix Assisted Laser Desorption/Ionization. The sample for MALDI is uniformly mixed in an exceedingly lots of abundance of matrix. The matrix absorbs the ultraviolet tlight of wave length 337nm of nitrogen optical maser light and converts it to heat energy. In MALDI small a part of the matrix heats in many nano seconds and is volatilized along with the sample. Ions with same m/z ratio but higher kinetic energy penetrate deeper into the reflector, delaying their time of arrival at the reflector relative to the slower low-energy ions. The main advantages of MALDI includes used for study of polymers, proteins, peptides, Improved resolution, increase in mass accuracy, matrix disperses large amounts of energy absorbed by the laser, minimizes fragmentation of the molecule and permits analysis of molecular weight over 10,000 Da.

Related journals of MALDI
Journal of Glycomics & Lipidomics, Journal of Chromatography & Separation Techniques, Journal of Analytical & Bioanalytical Techniques, Journal of Medical Microbiology, Medical Mycology, American Society for Mass Spectrometry