Journal of Leukemia
Open Access

Mast Cell Leukemia

Mast cell leukemia (MCL) is a very rare form of aggressive systemic mastocytosis accounting for < 1% of all mastocytosis. It may appear de novo or secondary to previous mastocytosis and shares more clinicopathologic aspects with systemic mastocytosis than with acute myeloid leukemia. Symptoms of mast cell activation-involvement of the liver, spleen, peritoneum, bones, and marrow-are frequent.

The common phenotypic features of pathologic mast cells encountered in most forms of mastocytosis are unreliable in MCL.

Related Journals of Mast Cell Leukemia