ISSN: 0974-276X
Accelerating development of technology in the field of proteomics has led to the study of protein structure and function, its expression in normal cell and a diseased cell. The microarray technology has enabled the study of changes in mRNA. Molecular and cellular proteomics allows knowing the post-translation modification of the proteins and the contribution to the gene expression. Along with the other branches of science like biochemistry, molecular genetics, cell biology with proteomics help in studying the cancer metastasis and improvement of the methodologies. Thus, helping researchers in the discovery of biomarkers and pathogenetic studies. A measurable biological indicator of a specific biological state which has the potential to improve the patient survival rate affectively is biomarkers. These biomarkers are used for diagnostic, predictive, prognostic and for pharmacodynamics purposes.
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