Translational Medicine
Open Access

Molecular Targeted Therapies

Molecular Targeted Therapies uses drugs to target specific molecules (for example, proteins) on the surface of or inside harmful cells. These molecules help send signals that tell cells to grow or divide. By targeting these molecules, the drugs stop the growth and spread of harmful cells while limiting harm to normal cells. Targeted therapies use different types of drugs, and each drug works differently.

Researchers are studying different targeted therapies in animals (preclinical testing) and in humans (clinical trials). However, few targeted therapies have been approved for treatment. Targeted therapies may eventually prove to be more effective and less harmful than current treatments.