Mass Spectrometry & Purification Techniques
Open Access

Tandem Mass Spectrometry

Tandem mass spectrometery is a specialized instrument that detects molecules by measuring their weight. Tandem mass spectrometers measure weight electronically and display results in the form of a mass spectrum. A mass spectrum is a graph that shows each specific molecule by weight and how much of each molecule is present. Mass Spectrometer measure mass/charge ratio of an ion. Tandem Mass Spectrometry mainly generates partial N and C-terminal peptides. Spectrum consists of different ion types because peptides can be broken in several places. Tandem Mass Spectrometer further breaks the peptides down into fragment ions and measures the mass of each piece. The advantages of tandem mass spectrometry are the sequences that are not necessarily in the database and an additional similarity search step using these sequences may identify the related proteins in the database.

Related journals of Tandem mass spectrometry
Journal of Analytical & Bioanalytical Techniques, Journal of Bioanalysis & Biomedicine, Journal of proteome research, The American Society for Mass Spectrometry, International Journal of Mass Spectrometry, Royal Society of Chemistry