Transcriptomics: Open Access
Open Access

Transcriptional Regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. It is estimated that the human genome encodes approximately 25,000 genes, about the same number as that for corn and nearly twice as many as that for the common fruit fly. Even more interesting is the fact that those 25,000 genes are encoded in about 1.5% of the genome. So, what exactly does the other 98.5% of our DNA do? While many mysteries remain about what all of that extra sequence is for, we know that it does contain complex instructions that direct the intricate turning on and off of gene transcription.

Related Journals of Transcriptional Regulation

Transcriptomics, Gene Technology, Journal of Genetic Syndromes & Gene Therapy, Human Genetics & Embryology, Gene, Gene Expression, Gene Expression Patterns, Genes and Genetic Systems, Genes and Genomics