Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
He Chao
China
Review Article
The Influence of Pregnancy on the Prognosis of Endometrial Atypical Hyperplasia and Adenocarcinoma with Assisted Reproductive Technology after Fertility-Sparing Therapy: A Systematic Review and Meta-Analysis
Author(s): Lu-ping Yu, Shi-yi Zhao, He Chao and Ying Liu
Lu-ping Yu, Shi-yi Zhao, He Chao and Ying Liu
Objective: To evaluate live birth rates and the influence of pregnancy on the prognoses of young women (<40 years old) with early-stage endometrial cancer (EC) and atypical complex hyperplasia (AH) who were treated by conservative management followed by assisted reproductive technology (ART).
Methods: A meta-analysis of observational studies with a random-or fixed-effects model as appropriate.
Results: A study of 527 women from 23 studies included 201 women to assess how prognosis might be influenced by pregnancy. Analysis of no pregnancy studies as the reference group pointed to a statistically significant positive association between pregnancy and decreased risk for recurrence (RR) of 0.56, 95% confidence interval (CI): 0.37-0.84. Eighteen studies including 104 women enabled determination of live birth rates o.. View More»
DOI:
10.4172/2375-4508.1000153