Virology & Mycology
Open Access
ISSN: 2161-0517
ISSN: 2161-0517
Department of Pharmacy, Shivajirao Pawar College of Pharmacy, Newasa, Maharashtra, India
Research Article
Treatment of Super Facial Mycoses Research: Ebercanozole/Ebernet
Author(s): Ghodke Krushna* and Somnath Kale Shital Rajendra
In vitro and preclinical studies have demonstrated better therapeutic efficacy with eberconazole than clotrimazole and ketoconazole. The objective of current investigation was to study the degradation behavior of eberconazole nitrate and mometasone furoate under different International Conference on harmonization recommended stress condition using reverse phase high performance liquid chromatographic method and to establish validated stability indicating high performance liquid chromatographic method to determine purity of eberconazole nitrate and mometasone furoate in presence of its impurities, forced degradation products and placebo in pharmaceutical dosage forms. Topical application of eberconazole was well tolerated in preclinical studies without any report of delayed hypersensitivity or photosensitivity reactions. There were no phototoxic effects. There was no significa.. View More»
DOI:
10.35841/2161-0517.22.11.221