Clinical & Experimental Cardiology

Clinical & Experimental Cardiology
Open Access

ISSN: 2155-9880

+44 1300 500008

A descriptive multi-centered study of clinical and epidemiological profile of patients with acute coronary syndrome (ACS) without significant stenosis on angiography


5th International Conference on Clinical & Experimental Cardiology

April 27-29, 2015 Philadelphia, USA

Alberto Giraldez Valpuesta1, Alejandro Gutiérrez Barrios1, Santiago Camacho Freire1, Livia Gheorghe2, Sergio Gamaza Chulian1, Antonio Agarrado Luna1, Manuel Sancho Jaldón2 and Javier Benezet Mazuecos1

Posters-Accepted Abstracts: J Clin Exp Cardiolog

Abstract :

Background: ACS patients with normal or near normal coronary arteries (NONCA) have traditionally been associated with a more favorable risk profile (young woman with few cardiovascular risk factors) and with an excellent prognosis, although in recent years it is being shown an increased risk clinical profile and a not so benign course. Methods: Descriptive multi-centered study of clinical and epidemiological characteristics of 68 patients with ACS without severe angiographic lesions Results: 52% were women. Mean age 62.2 years ± 12. Regarding risk factors: smoking 44%; hypertension 71%, 34% Diabetes Mellitus; hypercholesterolaemia 35%; cocaine use 2%; Other comorbidities: COPD 13%; CKD 17%, obesity (BMI> 30) 47%, atrial fibrillation 10.4%; systolic ventricular dysfunction (EF <50%) 5.6%, although 22% had any regional wall motion abnormalities Regarding the clinical event (ACS), 11% of patients presented some degree of heart failure, 56% had ST segment depressión and/or T-wave changes, 15% ST-segment (transient) elevation and 25% of patients presented with an elevation of cardiac troponins Stress testing was performed in 35% of patients, being positive in 71% of cases Regarding coronary angiography, 53% had mild to moderate lesions, the left anterior descending being the most affected artery (32%) Regarding. treatment, 62% of patients were receiving statins at discharge; 60% Betablockers, 75% ACE inhibitors; 71% antiplatelets agents and 7% anticoagulants Conclusion: We found in our study that patients with ACS without angiographic lesions present a cardiovascular risk profile and clinical characteristics similar to patients with traditional ACS

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