Translational Medicine
Open Access
ISSN: 2161-1025
ISSN: 2161-1025
Ren Chongxi
Hebei Medical University, China
Scientific Tracks Abstracts: Transl Med
Treatment of human metastatic colorectal cancer (mCRC) remarkably changed over the past two decades. The use of novel therapies and more complex treatment strategies have contributed to progressively increase the median life expectancy of patients up to approximately 30 months. Although traditional cytotoxic chemotherapy and newly targeted therapy are now available for use in treating patients with mCRC, the optimal treatment strategy remains unknown. Currently, therapeutic strategies for mCRC patients are based on a continuum of care whereby patients are exposed throughout the course of their disease to different active drugs, the therapy is personalized according to the need for rapid response and the burden of disease and RAS status, drugs are often reintroduced if they showed activity in previous line of therapy, and extremely importantly, maintenance chemotherapy and/or intermittent therapy are considered. Here, we review available data for the use of continuum of care strategy in mCRC, and regard it as a promising treatment strategy.
Ren Chongxi graduated from Hebei Medical University and completed his MD from QingDao University School of Medicine. He is the Director of Department of Surgical Oncology, Hebei Medical University. He has published more than 20 papers in reputed journals and has been serving as an Editorial Board Member of repute.
Email: rcxvip@outlook.com