Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
+44 1478 350008
ISSN: 2161-0495
+44 1478 350008
Isaiah Nnanna Ibeh, Akanu N, Mkpa A M, Isitua C C and Ogefere H O
Scientific Tracks Abstracts: J Clinic Toxicol
T he acquired immunodeficiency syndrome (AIDS) pandemic continues to inflict heavy death toll on human population worldwide with no cure yet documented. The burden of the disease remains highest in the least developed nations of the world where some of the chemotherapeutic agents already developed to combat the disease may be very scarce or not affordable ; thus, creating the need for search for a definitive cure which must be cheap and affordable. The present study was on a herbal remedy called DXL (Deconcuction X-Liquid) which was evaluated for its anti-human immunodeficiency virus potential by administering it to HIV positive cases (n = 5) over a period of 30 days. The dosage was chosen by making reference to the Lethal Dose Fifty (LD 50 ) established elsewhere in another study. The HIV positive individuals exposed to DXL experienced ceasation of constant frontal headaches, intense internal heat and muscular wasting within 14 days and progressing to a body weight gain of 5.8kg and an almost doubling of the CD 4 T-Cells number from 532.17 � 15.05 cells / ml to 932.73 � 15.05 cells / ml at the end of 30 days. Exposure to DXL also enhanced mean cell haemoglobin in the HIV positive individuals. The mechanism of action of DXL may include stoppage of CD 4 T-Cells destruction and restoration of normal metabolic activities in an HIV infected person. These findings suggest that DXL may be an intervention tool in the cycle of HIV infection
Isaiah Nnanna Ibeh became a qualified Medical Laboratory Scientist in 1980 and thereafter obtained a Masters and PhD degrees in Immunology & Immunochemistry and Food & Industrial Microbiology respectively in 1988 and 1992 all from the University of Benin, Nigeria. He received a commonwealth Technical Scholarship to study in University of London 1986. He was awarded a Postdoctoral Research Fellowship by the Third World Academy of Science (TWAS), Italy, in 1995. He was a Postdoctoral Research Fellow of the Council of Scientific an Industrial Research (CSIR) of India (1995-1996). He has produced over 30 Masters of Science (M.Sc.) degree and 10 Doctor of Philosophy (Ph.D) degree holders. He worked for a year as a Medical Laboratory Scientist in the University of Benin Teaching Hospital before relocating to Microbiology Department of University of Benin where he worked as a Laboratory Technologist for 10 years. He was appointed Lecturer 1 in 1993 and rose through the ranks to a full Professor of Microbiology in 2003. His areas of interests are environmental toxins (mycotoxins), immunomodulation, food toxicology and ethnomedicine. He has over 100 scholarly publications in reputable local and international journals. He is a member of several Boards and Committees of University of Benin