Journal of Antivirals & Antiretrovirals
Open Access

Lipase-catalyzed synthesis of a functional xylitol ester of 7,10-dihydroxy-8(E)-octadecenoic acid

Joint Event on 4^th International Conference on Antimicrobials, Multiple Drug Resistance & Antibiotics Resistance & 4^thInternational Conference on Antibiotics R&D, B2B

April 20-21, 2018 Las Vegas, USA

Yeon-Jung Lee, Ji-Sun Moon, Hyung-Geun Lee, Ching T Hou and Hak-Ryul Kim

Kyungpook National University, Korea
USDA, USA

Posters & Accepted Abstracts: J Antivir Antiretrovir

Abstract :

Hydroxy fatty acids have been widely studied because they have various biological properties that can be utilized in many industries, compared with other types of fatty acids. Among the hydroxy fatty acids, our research group focused on 7,10-dihydroxy-8(E)-octadecenoic acid (DOD). We confirmed that the strong antibacterial activities of DOD against foodborne pathogenic bacteria and plant pathogenic bacteria. Saccharide�fatty acid esters are important biodegradable emulsifiers in foods, cosmetics, and pharmaceuticals, hence, we focused on enzymatic synthesis of DOD-saccharide esters for industrial utilization of DOD. Several saccharides were screened as a substrate for esterification with DOD. As a result, DOD xylitol ester was successfully produced at 50 with stirring at 200rpm for 24 hours in the presence of lipozyme RMIM as enzyme, and t-butyl alcohol as solvent. Its structure was confirmed by GC/MS.

Biography :

Yeon-Jung Lee is a graduate student in School of Food Science and Biotechnology, Kyungpook National University in Daegu Korea.
Email:hakrkim@knu.ac.kr