Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
+44 1300 500008
ISSN: 2155-9880
+44 1300 500008
Starry Homenta Rampengan, Jimmy Posangi, Julius Lolombulan, Joedo Prihartono, Suzanna Immanuel, Trina Tallei and Victor Pijoh
Sam Ratulangi University, Indonesia
State University of Manado, Indonesia
University of Indonesia, Indonesia
Posters & Accepted Abstracts: J Clin Exp Cardiolog
Background: Helicobacter pylori (H. pylori) colonize and infect gastric mucosa which might lead to chest discomfort. It is assumed that the products of H. pylori (cytokines, cytotoxic) denudate and erode the coronary artery plaque; therefore, it is suspected that H. pylori infection might be associated with inflammatory response of acute myocardial infarction (AMI), although the assumption is still controversial. Aim: Aim of this study is to identify the impact of H. pylori toward the severity and type of AMI; and the number of risk factor for chronic heart disease (CHD) in AMI patients. Method: Our study was a prospective cohort study that was conducted among patients with AMI at the hospitals in Manado city and its surrounding areas between 2015-2016. Data collection was carried out by filling in questionnaires, serology testing to identify antigen of H. pylori and conducting echocardiography in patients with AMI. Data was analyzed using SPSS program version 23.0. Results: There was no significant impact of H. pylori infection toward the severity of AMI (p=0.713) and the number of CHD risk factors (p=0.087); however, the type of AMI and H. pylori infection showed a significant association (p=0.017). STEMI patients tended to have H. pylori infection. Conclusion: No significant impact of H. pylori infection toward the severity of AMI and the number of CHD risk factors was found; however, there was a significant association between type of AMI (STEMI) and H. pylori infection.
Starry Homenta Rampengan has completed his PhD and Post-doctoral studies from University of Indonesia. He is Director of Jade Cardiovascular Clinic in North Sulawesi, Indonesia and Consultant Cardiologist, Interventionist at Siloam Hospital Manado and Kandou Hospital Manado, North Sulawesi, Indonesia. He has published more than 20 papers in journals.
Email: starry8888@yahoo.com