Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
+32 25889658
ISSN: 2155-9600
+32 25889658
Ali Alyami
Curtin University, Australia
Scientific Tracks Abstracts: J Nutr Food Sci
There is increasing interest in the extra-skeletal effects of vitamin D on chronic diseases including CVD. The objective of this study
was to determine whether circulating lipids, systemic inflammation and biomarkers of endothelial cell activation varied across
vitamin D status of older Australians. One hundred and one participants were proportionately sampled across tertile (T1=lowest,
T2=middle, T3=highest) of 25(OH)D3 from a larger cohort of free living older adults. Blood samples after an overnight fast were
assayed for PTH, insulin, TAG, total cholesterol and lipid fractions. Markers of systemic inflammation and endothelial activation
included hsCRP, TNF- �±, hepatocyte growth factor (HGF), P-selectin and soluble vascular cell adhesion molecule (sVCAM) amongst
others. Eighty three participants (48 women, 35 men) aged 65�±7.7 years; BMI 28�±4.5 kg/m2 with complete data entered the analysis.
A general linear model multivariate analysis with a backward elimination stepwise procedure was performed (SPSS version 22). The
final model built based on a parsimonious model, which included age, gender, BMI, McAuley�s index as confounders but excluded
season, medications and PTH, indicated that there were significant differences across vitamin D tertile in TC (T1>T3, p=0.003),
LDL-C (T1>T3, p=0.005), HGF (T1 Ali Alyami is a Clinical Dietitian, obtained his Bachelor’s degree from King Saud University 2004 and Master’s degree from Canberra University in 2011. He is currently pursuing his PhD at Curtin University, Perth, Western Australia. Email: yami.ali2002@gmail.comBiography :