Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Mohamed Samir Abdelghafar
Tanta University Faculty of Medicine,
El geish street, Tanta
Egypt
Research Article
Determination of Optimal PEEP by Carbon Dioxide Production (VCO2) in ARDS Patients
Author(s): Mohamed Samir Abdelghafar and Zahretelwady Mohamed Salaheldin MohamedMohamed Samir Abdelghafar and Zahretelwady Mohamed Salaheldin Mohamed
Background: The use of PEEP is a corner stone in the management of ARDS. Several methods were investigated to determine the optimal PEEP. However, no method is considered gold standard. The study investigated whether the use of VCO2 to determine optimal PEEP value in ARDS patients improves oxygenation, alveolar ventilation and static compliance compared to ARDSNet FiO2-PEEP combination.Patients and methods: This prospective randomized controlled study was conducted at a tertiary university hospital ICU including sixty mechanically ventilated ARDS patients. Patients were randomized between two groups; group A, where PEEP was titrated using FiO2-PEEP combination and group B, where PEEP was titrated according to VCO2. In this group, PEEP was increased in increments of 2 cm H2O every 20 minutes .. View More»
DOI:
10.4172/2155-6148.1000874