Journal of Clinical Toxicology
Open Access

Peter S Kruger

Publications

• Case Report
  Severe Toxicity with Guanidine Thiocyanate Ingestion
  Author(s): Colin B Page, Peter S Kruger, Goce Dimeski and James Walsham Colin B Page, Peter S Kruger, Goce Dimeski and James Walsham
  
  Objective: To describe the toxicity of deliberate guanidine thiocyanate ingestion and it's treatment including dialysis. Case report: A 52-year-old male presented to hospital with abdominal pain after giving a history of ingesting bottled water. His initial vital signs and examination were normal. Soon after the patient became confused and agitated, necessitating intubation and ventilation for presumed encephalitis. His chloride was unmeasurable and the ionised calcium was low at 0.59 mmol/L (reference range [RR] 1.15-1.32 mmol/L). His pH and osmolar gap were normal. Analysis of the ingested water on two chemistry analysers gave discrepant chloride readings (129 mmol/L and 49 mmol/L) suggesting interference from a cross reacting analyte, which subsequently was proven to be thiocyanate with a concentration of 1485mg/L and 538mg/L in the b.. View More»
  DOI: 10.4172/2161-0495.1000325

  Abstract PDF

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